Prof. Stephen Ferguson
Pre-clinical mechanical evaluation of a novel spinal implant
Lower back pain is one of the most prevalent health issues in Switzerland, with severe socio-economic consequences and a leading cause of reduced work performance. Approximately 20% of spinal fusion surgeries performed using off-the-shelf implants result in the surgical outcome being compromised post-operatively, often requiring one or more revision surgeries to address the associated pain. The Laboratory of Orthopedic Technology has recently developed a novel spinal implant using topology optimization, which is currently undergoing a feasibility study for clinical applications. We are seeking a master’s student who is passionate about medical devices and mechanical design and testing to join us for a master thesis. In this role, you will gain insight into the spinal surgery process, receive input from surgeons, and contribute to the mechanical testing of the implant on human cadaveric spine. Objectives: • Perform the CT scan on human cadaveric vertebrae • Evaluate the influence of implant placement/location variability • Mechanical testing on the implant and failure mode analysis • Develop surgical tools if needed • Write related SOPs and testing report Your Profile: • Hands-on and detail-oriented, need to work with human cadaveric bones. • Experience with SolidWorks or Fusion 360, as well as Python or Matlab. • Need to have Hepatitis B Vaccine to be able to work in BSL 2 level labs
Keywords
implant, medical device, mechanical testing, clinical application
Labels
Master Thesis
Contact Details
More information
Published since: 2025-06-10 , Earliest start: 2025-06-23 , Latest end: 2026-01-30
Organization Bone Pathologies and Treatment
Hosts Du Xiaoyu
Topics Medical and Health Sciences
Experimental and Numerical Investigation of Direction-Dependent Flow Resistance in Engineered Geometries
Controlling fluid flow is essential in various natural and engineering systems, with geometry playing a fundamental role in shaping fluid behavior. However, the interaction between geometry and flow behavior remains a complex phenomenon, primarily governed by the flow regime and fluid material properties. Certain geometries, whether naturally occurring or engineered, induce direction-dependent flow resistance, causing variations in velocity and flow rate in opposite directions. One well-known example of such engineered geometries is the Tesla valve—a passive device without moving parts, designed to create asymmetric flow resistance, particularly at high Reynolds numbers. This structure acts like a fluidic diode, offering greater resistance to flow in one direction by generating turbulent vortices and flow separations while allowing smoother movement in the opposite direction. This effect is quantified by diodicity, which represents the ratio of pressure drop in the reverse direction to that in the forward direction, providing a measure of the valve's asymmetric resistance. However, this direction dependence is limited at lower velocities. We have designed two sets of geometries that effectively induce directional flow resistance within high and low fluid flow velocities. This Master’s thesis project aims to experimentally investigate the impact of different flow obstruction designs on direction-dependent resistance in rectangular channels and semicircular arc segments. The student will, together with their direct supervisor, design and construct an experimental setup for the reliable measurement of flow and diodicity. This project offers an excellent opportunity to gain expertise in fluid dynamics, experimental testing, numerical modeling, and additive manufacturing, with applications in biomedical systems. Students with a background in mechanical engineering, fluid dynamics, or related fields are encouraged to apply. Prior experience with COMSOL Multiphysics is beneficial but not mandatory.
Labels
Master Thesis
Contact Details
More information
Published since: 2025-04-15 , Earliest start: 2025-06-01 , Latest end: 2025-12-01
Organization Musculoskeletal Biomechanics
Hosts Mosayebi Mahdieh
Topics Engineering and Technology